Electrophysiological Neuroimaging using sLORETA Comparing 12 Anorexia Nervosa Patients to 12 Controls

Andy R. Eugene, Jolanta Masiak, Jacek Kapica


Anorexia Nervosa (AN) is characterized by Diagnostic and Statistical Manual of Mental Disorders Volume 4 (DSM IV), as one’s refusal to maintain a body weight that is above the calculated limit, which is determined by an algorithm involving one’s height and weight. As more
emphasis in society is placed on one’s body image and appearance there has been an increase in the prevalence of this disease. Previously, the sole diagnostic imaging modality was fMRI. Studies determined that there was reduced blood flood in the Parahippocampal Gyrus, and Left Fusiform Gyrus, of those afflicted with AN. Electroencephalography (EEG) was utilized as an alternative imaging modality that was more cost effect. It was determined that the activated regions localized
on the fMRI study coincided with those highlighted on the EEG report and previous fMRI studies. The goal of this study was to determine a more cost effective way to earlier detect a diagnosis of AN. The desired outcome would be for patients afflicted with AN to be diagnosed and treated at an earlier stage, increasing their overall long-term survival.


Anorexia; Parahippocampal Gyrus; Fusiform Gyrus; sLORETA; Neuroimaging

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