BRAIN. Broad Research in Artificial Intelligence and Neuroscience

Volume: 16 | Issue: 3

Gender Differences in Neural Decision-Making: Cognitive Mechanisms, Educational Implications, and the Role of AI

Ioannis Mavroudis - Leeds Teaching Hospitals, NHS Trust, Leeds, United Kingdom; Aristotle University of Thessaloniki, Greece (GB), Foivos Petridis - Aristotle University of Thessaloniki (GR), Alin Ciobica - Alexandru Ioan Cuza University of Iasi; Appolonia University of Iasi; Grigore T. Popa University of Medicine and Pharmacy of Iasi; Academy of Romanian Scientists, Iasi Branch, Romania (RO), Gabriel Dascalescu - Alexandru Ioan Cuza University of Iași; Apollonia University of Iași, Romania (RO), Dimitrios Kazis - Aristotle University of Thessaloniki (GR), Antoneta Dacia Petroaie - Grigore T. Popa University of Medicine and Pharmacy of Iasi (RO), Otilia Novac - Grigore T. Popa University of Medicine and Pharmacy of Iasi (RO), Ioana Vata - Apollonia University of Iasi (RO), Bogdan Novac - Grigore T. Popa University of Medicine and Pharmacy of Iasi (RO),

Abstract

This narrative review synthesises evidence on gender-specific neurocognitive mechanisms underlying decision-making, emotional processing, and learning, and examines how AI-driven analyses can enhance personalised interventions. Drawing on EEG, fMRI, MEG, ERP, and eye-tracking studies, we show that women preferentially engage medial prefrontal and limbic networks, during semantic-relational and emotional tasks, whereas men recruit parietal-occipital circuits for visuospatial processing. Cultural context further shapes these patterns. AI applications, such as machine learning classifiers on neurophysiological data, improve the accuracy of gender-informed predictions, and support adaptive, neurodiversity-aware pedagogies. We conclude that integrating neuroscientific and AI insights can inform gender-sensitive educational design and decision-support systems, provided ethical safeguards against algorithmic bias and privacy breaches are in place. 

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DOI: http://dx.doi.org/10.70594/brain/16.3/17

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